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1. Affected Individual
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Obligatory
Must not donate.
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Discretionary
If more than 12 months from recovery, and either all markers are negative or if HB core antibody positive, HBsAg negative and anti-HBs has been documented at more than 100 iu/l at some time, accept.
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See if Relevant
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Additional Information
Hepatitis B is a serious viral infection that can lead to chronic liver disease and liver cancer (hepatoma).
Individuals who are chronically infected are sometimes referred to as 'carriers'. They often have no, or minimal, symptoms associated with their infection.
Cases are often linked to ethnicity (the condition is very common in many parts of the world and is spread from mother to baby) or to previous drug abuse.
Leaving 12 months from recovery before testing, provides additional security that the results will show if the infection is controlled and therefore unlikely to be passed on. (There is no requirement to monitor the anti -HBs level, but it must have been documented at >100iu/l at some point).
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Update Information
This entry was last updated in:
DSG-WB Edition 203, Release 01.
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Reason for Change
Affected Individual' and 'History of Infection' have been merged.
'Known Carriers' has been removed as these individuals are 'Infected'. The term 'Carrier' may cause confusion.
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2. Current or Former Sexual Partner of Affected Individual
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Obligatory
Must not donate.
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Discretionary
Obtain history (including time from last sexual contact) and:
a) If less than 12 months from last sexual contact:
If HB core antibody positive, HBsAg negative and anti-HBs has been documented at more than 100 iu/l at some time, accept.
b) If more than 12 months from last sexual contact:
If negative for all markers or, HB core antibody positive, HBsAg negative and anti-HBs has been documented at more than 100 iu/l at some time, accept.
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See if Relevant
Blood Safety Entry
Hepatitis B - 4. Immunization, below.
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Additional Information
There is no requirement to monitor the anti-HBs level. Any further exposure to HBV would be expected to boost the anti-HBs level and provide protection against HBV.
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Information
This entry is compliant with the Blood Safety and Quality Regulations 2005.
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Update Information
This entry was last updated in:
DSG-WB Edition 203, Release 01.
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Reason for Change
The '˜Current Sexual Partner of Affected Individual' and 'Former Sexual Partner of Affected Individual' guidance has been merged.
The 'Discretionary' and 'Additional Information' entries have been modified to allow former sexual partners of infected individuals to be accepted (if immune and complying with the requirements in the 'Additional Information' section) before 12 months have passed since the last sexual contact.
This brings '˜Former Sexual Partner of Affected Individual' advice into line with the requirements for 'Current Sexual Partner of Affected Individual'.
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3. Person Currently or Formerly Sharing a Home with an Affected Individual
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Obligatory
Must not donate.
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Discretionary
Obtain history (if no longer sharing include the time since sharing ceased) and:
a) If still sharing or it is less than 12 months since sharing ceased:
If HB core antibody positive, HBsAg negative and anti-HBs has been documented at more than 100 iu/l at some time, accept.
b) If more than 12 months since sharing ceased:
If negative for all markers or, HB core antibody positive, HBsAg negative and anti-HBs has been documented at more than 100 iu/l at some time, accept.
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See if Relevant
Hepatitis B - 4. Immunization, below.
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Additional Information
There is no requirement to monitor the anti-HBs level. Any further exposure to HBV would be expected to boost the anti-HBs level and provide protection against HBV.
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Information
This entry is compliant with the Blood Safety and Quality Regulations 2005.
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Update Information
This entry was last updated in:
DSG-WB Edition 203, Release 01.
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Reason for Change
There has been a modification to 'Discretionary' and to 'Additional Information'. This brings it into line with the requirements for 'Current Sexual Partner of Affected Individual'.
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4. Immunization
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Obligatory
a) Known Exposure:
Must not donate.
b) No Known Exposure:
Must not donate if:
Less than seven days after the last immunization was given.
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Discretionary
a) Known Exposure:
If more than 12 months from immunization, and either all markers are negative or HB core antibody positive, HBsAg negative and anti-HBs has been documented at more than 100 iu/l at some time., accept.
b) No Known Exposure:
If more than seven days after the last immunization was given, even after intramuscular immunoglobulin, accept.
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See if Relevant
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Additional Information
Immunization post exposure may be with specific anti-HB immunoglobulin as well as with HBsAg.
There is no requirement to monitor the anti-HBs level.
May be combined with hepatitis A immunization.
Sensitive assays for HBsAg may be positive following recent immunization. This is why a seven day deferral is required.
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Update Information
This entry was last updated in:
DSG-WB Edition 203, Release 01.
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Reason for Change
The layout has been changed to improve clarity.
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Donor Information
If you wish to obtain more information regarding a personal medical issue please contact your National Help Line.
Please do not contact this web site for personal medical queries, as we are not in a position to provide individual answers.
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