Latest Updates
Better Blood Transfusion TOOLKIT

Document Library updates
A new page with papers supporting the Change Notifications has been created.
June 2013
The JPAC paper on Deviations from the specified storage temperature for Fresh-Frozen Plasma (FFP) whilst in its frozen state has been updated 'General Documents'
The JPAC Position Statement on Chikungunya Virus has been updated
May 2013
Publication of Change Notification 01 - 2013
February 2013
Publication of Change Notification 27-29 - 2012
Publication of supporting paper Sickle Cell Trait and Apheresis
Publication of supporting paper Decompression illness
The JPAC paper on Shelf-life of Frozen Plasma Components Following Thawing has been added to 'General Documents'
December 2012
The JPAC Position Statement on Methylene Blue-Treated Plasma has been added
The JPAC Position Statement on Blood donor selection to minimise risk of transfusion transmissible infectious agents entering the blood supply has been updated
November 2012
The JPAC Position Statement on Creutzfeldt-Jakob Disease has been updated
The JPAC Position Statement on Granulocyte Therapy has been updated
The JPAC Position Statement on The estimated risk that a donation entering the blood supply is a potentially infectious window period donation: risks specific for HBV, HCV and HIV in the UK, 2010 - 2011 has been updated
October 2012
The JPAC Position Statement on Creutzfeldt-Jakob Disease has been updated
Publication of Change Notification 20-24 - 2012
Publication of Change Notification 25 - 2012
Publication of Change Notification 26 - 2012
August 2012
Publication of Change Notification 19 - 2012
June 2012
The JPAC Position Statement on Emerging Infections has been updated
Publication of Change Notification 06-18 - 2012
Publication of supporting paper Recommendations on a change to the Donor Selection Guidance for Pregnancy
Publication of supporting paper Toxoplasmosis DSG entry
May 2012
The JPAC Position Statement on The estimated risk of HBV, HCV and HIV potentially infectious donations entering the UK blood supply due to the window period of tests in use, 2008 – 2010 has been updated
April 2012
The JPAC paper on Validation of Blood Component Quality Following Prion Removal Procedures for Red Cell Components has been updated 'General Documents'.
The JPAC paper on Evaluation of novel platelet components has been removed from 'General Documents'
The JPAC Position Statement on Chikungunya Virus has been updated
The JPAC paper on Evaluation of Efficacy of Prion Removal Filters has been updated 'General Documents'
March 2012
Publication of Change Notification 03-05 - 2012
The JPAC Position Statement on Cytomegalovirus (CMV) has been withdrawn following the publication of the Government’s Advisory Committee on the Safety of Blood, Tissues and Organs (SaBTO) Position Statement on CMV
The JPAC Position Statement on West Nile Virus (WNV) has been updated
February 2012
Publication of Change Notification 01-02 - 2012
January 2012
Publication of Change Notification 22 -27 - 2011
Publication of supporting paper Recommendations on Donor Height and Weight
December 2011
Publication of Change Notification 20 - 2011
Publication of Change Notification 21 - 2011
Publication of supporting paper Risk assessment for immunosuppression and corneal donation
November 2011
Publication of Change Notification 16 - 2011
Publication of Change Notification 17 - 2011
Publication of Change Notification 19 - 2011
The Blood Safety Leaflet Information - this version has been updated and contains information which applies to England, Scotland and Wales only
The Blood Safety Leaflet Information - this version applies to Northern Ireland Only
The JPAC Position Statement on 2011 Blood donor selection to minimise risk of transfusion transmissible infectious agents entering the blood supply has been added
October 2011
The JPAC paper on Deviations from the specified storage temperature for Fresh-Frozen Plasma (FFP) whilst in its frozen state has been added to 'General Documents'
Publication of Change Notification 18 - 2011
The JPAC Position Statement on West Nile Virus (WNV) has been updated
September 2011
Publication of Change Notification 14 - 2011
Publication of supporting paper Recommendation for a change to the Live Tissue Donor Selection guidance for Malaria
August 2011
Publication of Change Notification 11 - 2011
Publication of Change Notification 12 - 2011
Publication of Change Notification 13 - 2011
Publication of Change Notification 15 - 2011
July 2011
The JPAC paper on List of Evaluations has been updated 'General Documents'.
The JPAC Position Statement on Emerging Infections has been added.
June 2011
Publication of Change Notification 1 - 5 - 2011
Publication of Change Notification 6 - 9 - 2011
March 2011
The JPAC Position Statement on CMV Seronegative vs. Leucodepleted blood components for at risk recipients has been updated
February 2011
Publication of Change Notification 12 - 2010
Publication of Change Notification 13 - 2010
The JPAC Position Statement on Chikungunya Virus has been updated
January 2011
Amendment to Change Notification No.7 - 2010
Publication of Change Notification 14 - 2010
December 2010
The JPAC Position Statement on Granulocyte Therapy has been updated
November 2010
Publication of Change Notification 11 - 2010
Publication of supporting paper Long term storage of tissue products v1
Publication of Change Notification 8 - 2010
Publication of Change Notification 7 - 2010
September 2010
The JPAC Position Statement on Estimated infection risk - Blood has been added
Publication of Change Notification 9 & 10 - 2010
The JPAC Position Statement on Creutzfeldt-Jakob Disease has been updated
Diary of Educational Events has been updated.
June 2010
Publication of Change Notification 6 - 2010
Publication of supporting paper Addition to 14.5.1 of the Red Book to allow rare antisera to be used in investigations.
April 2010
The JPAC Position Statement on Creutzfeldt-Jakob Disease has been updated
March 2010
The JPAC Position Statement on West Nile Virus (WNV) has been updated
The JPAC Position Statement on Blood donor selection has been updated
Publication of Change Notification 2 - 5 - 2010
January 2010
The JPAC paper on 'Deviations from 4 oC temperature storage for red cells: Effect on viability and bacterial growth' is now available as a PDF download from the library page 'General Documents'.
The JPAC paper on 'Validation of Blood Component Quality Following Prion Removal Procedures for Red Cell Components' has been updated 'General Documents'.
Position statement Severe Acute Respiratory Syndrome (SARS) reconfirmed.
Publication of Change Notification 1 - 2010
Publication of supporting paper HbS testing neonatal red cell components
December 2009
Publication of Change Notification 28 - 31 - 2009
Publication of Change Notification 32 - 35 - 2009
November 2009
Commission Directive 2009/135/EC added to EU Directives & Regulations
Publication of Position Statement Chikungunya Virus
Publication of Position Statement Granulocyte Therapy
October 2009
Publication of Change Notification 27 - 2009
Publication of Change Notification 23 - 2009
Publication of Proposal to amend the content of 12.1.4 f) of the 2005 Guidelines.
The JPAC paper on 'The Use of G-CSF in Unrelated Volunteer Stem Cell Donors ' is now available as a PDF download from the library page 'General Documents' has been added.
September 2009
Publication of Change Notification 24 - 26 - 2009
August 2009
Publication of Change Notification 18 - 22 - 2009
July 2009
Publication of Change Notification 17 - 2009
Publication of Change Notification 16 - 2009
June 2009
Publication of Change Notification 12 - 2009
May 2009
Publication of Position Statement Creutzfeldt-Jakob Disease
Publication of Change Notification 8 to 10 & 13 to 15 - 2009
April 2009
Publication of Change Notification 11 - 2009
Pandemic Influenza - The UK Blood Services Plan has been updated.
February 2009
Publication of Change Notifications 03 to 07 - 2009
January 2009
The JPAC Position Statement on Granulocyte Therapy has been updated.
Publication of Change Notifications 01 & 02 - 2009
December 2008
The JPAC paper on 'Recommendations for removal of the upper age limit for regular whole blood and component donors' is now available as a PDF download from the library page 'General Documents' has been updated.
November 2008
The Summary and Report of the JPAC workshop on management of haemoglobin and iron in blood donors are available on this website.

Guidelines for the Blood Services in the UK
February 2012
Change Notification No.1 and 2 - 2012
Section 8.13 - Fresh Frozen Plasma, Leucocyte Depleted
Section 8.14 - Fresh Frozen Plasma, Methylene Blue Treated and Removed, Leucocyte Depleted
Section 8.15 - Cryoprecipitate, Leucocyte Depleted
Section 8.16 - Cryoprecipitate, Methylene Blue Treated and Removed, Leucocyte Depleted
Section 8.17 - Plasma, Cryoprecipitate Depleted, Leucocyte Depleted
Section 8.24 - Fresh Frozen Plasma, Neonatal Use, Methylene Blue Treated and Removed, Leucocyte Depleted
Section 8.25 - Cryoprecipitate, Methylene Blue Treated and Removed, Leucocyte Depleted
Section 8.30 - Cryoprecipitate Pooled, Leucocyte Depleted
Table 8.25 - Plasma components
Table 8.28 - Neonatal and infant plasma components
February 2011
Change Notification No.12 - 2010
Donor Care and Selection Chapters to replace Chapters 3 to 6
Chapter 3 - Care and selection of blood donors (including donors of pre-deposit autologous blood)
Chapter 4 - Premises and quality assurance at blood donor sessions
Chapter 5 - Collection of a blood donation
January 2011
Amendment to Change Notification No.7 - 2010
Section 8.32 - Granulocytes, Pooled, Buffy Coat Derived, in Platelet Additive Solution and Plasma
Change Notification No.14 - 2010
Section 22.7 - Testing of deceased donors
Section 22.11 - Release criteria
November 2010
Change Notification No.11 - 2010
Section 23.5 (Part 1) - General guidelines for tissue processing
Section 23.5 (Part 2) - General guidelines for tissue processing
Section 23.6 - Tissue storage
Section 23.9 - Additional guidelines for skeletal tissue retrieval and processing
Change Notification No.7 - 2010
Section 8.32 - Granulocytes, Pooled, Buffy Coat Derived, in Platelet Additive Solution and Plasma
June 2010
Change Notification No.6 - 2010
Section 14.5 - Test reagents and test systems
January 2010
Change Notification No.1 - 2010
Section 8.22 - Red Cells for Neonates and Infants, Leucocyte Depleted
Section 8.23 - Red Cells in Additive Solution for Neonates and Infants, Leucocyte Depleted
October 2009
Change Notification No.23 - 2009
Section 12.1 - Guidelines for reagent manufacture
July 2009
Change Notification No.17 - 2009
Section 8.23 - Red Cells in Additive Solution for Neonates and Infants, Leucocyte Depleted
Change Notification No.16 - 2009
Section 13.10.7 - Mandatory testing of blood donations
June 2009
Change Notification No.12 - 2009
Section 6.1 - Criteria for acceptance of donors
May 2009
Change Notification No.13 - 2009
Section 4.2 - Responsibility for blood collection
Change Notification No.10 - 2009
Section 22.7 - Testing of deceased donors
Change Notification No.9 - 2009
Section 22.3 - Medical and behavioural history
February 2009
Change Notification No.7 - 2009
Section 8.6 - Red Cells in Additive Solution, Leucocyte Depleted
Section 8.21 - Red Cells for Exchange Transfusion, Leucocyte Depleted
Change Notification No.6 - 2009
Section 8.28 - Irradiated components
Change Notification No.5 - 2009
Chapter 25 – Specification for the uniform labelling of blood and blood components
24.1.4 Referenced documents
25.5 Component labels
Chapter 28 - Specifications for blood pack base labels
28.1 Specification
Change Notification No.4 - 2009
Section 8.8 - Red Cells, Thawed and Washed, Leucocyte Depleted
Change Notification No.3 - 2009
Table 8.20 - Cryoprecipitate, methylene blue treated and removed, leucocyte depleted – additional tests
January 2009
Change Notification No.2 - 2009
Annex 1
Change Notification No.1 - 2009
Section 8.18 - Components Suitable for Use in Intrauterine Transfusion, Neonates and Infants Under One Year

Geographical Disease Risk Index
This page lists all changes to GDRI 001 after Release 01. This page constitutes
Section 2 of Appendix 1 - Changes to the Donor Selection Guidelines.
The changes are listed with the most recent change at the top.
Changes made with Release 19
Changes made to
Hungary, Croatia and Kosovo See Change Notification No. 25 - 2012
Changes made to
Algeria See Change Notification No. 26 - 2012
Changes made with Release 18
Changes made to
Iran, Iraq and Vietnam see Change Notification No. 20 - 2012
Changes made to
United States of America see Change Notification No. 21 - 2012
Search facility updated
Changes made with Release 17
Changes made to
West Bank, Gaza Strip, Tunisia, Greece, Serbia and Russia
see Change Notification No. 19 - 2012
Index items for West Bank, Gaza Strip and Palestine Occupied Territories, Palestine Occupied Territories and Transjordan added.
Changes made with Release 16
Changes made to
Cambodia, Columbia, Ecuador, Egypt, Ethiopia, Guatemala, India, Indonesia, Jamaica, Kenya, Laos, Namibia, Nicaragua, Suriname, Swaziland, Syria, Thailand, Vietnam and Zimbabwe
see Change Notification No. 14 - 2012
Index items for Sicily, Corsica and Koh Samui added.
Changes made with Release 15
Changes made to
Albania, Canada, Greece, Israel, Italy, Macedonia (FYR), Romania, Russia, Saint Pierre and Miquelon, Turkey and USA.
see Change Notification No. 04 - 2012
Changes made with Release 14 Issue 02
Malaria Risk updated for Morocco, Mauritius, Costa Rica, Peru, Panama, Sri Lanka, United Arab Emirates
Spelling of Malaria corrected on all Malaria Risk Category Subheadings.
Preliminaries Introduction page contact information has been updated.
Changes made with Release 14
Changes made to
Italy see Change Notification No. 19 - 2011
Changes made with Release 13
Changes made to
Macedonia, Russia and Turkey see Change Notification No. 18 - 2011
Changes made with Release 12
Changes made to
Albania, Israel and Russia see Change Notification No. 15 - 2011
Changes made with Release 11
Changes made to
Romania see Change Notification No. 12 - 2011
Greece see Change Notification No. 13 - 2011
Changes made with Release 10
Changes made to
see Change Notification No. 10 - 2010
Changes made with Release 09
Changes made to
Maldives see Change Notification No. 27 - 2009
Changes made with Release 08
Changes made to
Italy see Change Notification No. 25 - 2009
Canada, United States of America see Change Notification No. 26 - 2009
Changes made with Release 07
Changes made to
Italy see Change Notification No. 11 - 2009
This reverses the changes made with Change Notification No. 05 - 2007.
Changes made with Release 06
This release is the first implementation of the GDRI on the website. Layout and ordering of entries may differ on the website as compared to the Portable Document File (PDF) but there are no changes to the wording of any entries. Consequently no new PDF file is released.
Changes made with Release 05
Errata corrections made to
Italy see Change Notification No. 05 - 2007
Jamaica see Change Notification No. 20 - 2006
Changes made with Release 04
Introduction – Malaria: Airport stopovers see Change Notification No. 15 - 2007
Changes made with Release 03
Bahamas (The) see Change Notification No. 07 - 2007
Canada see Change Notification No. 08 - 2007
United States of America see Change Notification No. 08 - 2007
Changes made with Release 02
Egypt see Change Notification No. 02 - 2007
Ethiopia see Change Notification No. 02 - 2007

Whole Blood and Components
Invalid Link to Page
Bone Marrow and Peripheral Blood Stem Cell
This page lists all changes to TDSG-BM 203 after Release 02.
This pages constitutes Section 2 of Appendix 1 - Changes to the Donor Selection Guidelines.
Changes introduced with Release 03
A change was made to the version control definitions and all Issue numbering information removed.
Bleeding Disorder See Change Notification No. 18 - 2007
Changes introduced with Release 04
Blood Pressure - High See Change Notification No. 1 - 2008
Appendix 4 removed See Change Notification No. 5 – 2008
This update also corrects an error where commas did not display in the A-Z topics content on the website.
Changes introduced with Release 05
Tamiflu® (oseltamivir) See Change Notification No. 30 - 2009
Relenza® (zanamivir) See Change Notification No. 31 - 2009
Changes introduced with Release 06
Acupuncture See Change Notification No. 33 - 2009
Complementary Therapy See Change Notification No. 35 - 2009
Changes introduced with Release 07
Body Piercing See Change Notification No. 02 - 2010
Inoculation Injury See Change Notification No. 04 - 2010
Endoscopy See Change Notification No. 05 - 2010
Changes introduced with Release 08
West Nile Virus (WNV) See Change Notification No. 09 - 2010
Changes introduced with Release 09
Immunization - Live See Change Notification No. 06 - 2011
BCG See Change Notification No. 07 - 2011
Infertility See Change Notification No. 08 - 2011
Sexually Transmitted Disease See Change Notification No. 09 - 2011
Changes introduced with Release 10
West Nile Virus (WNV)See Change Notification No. 11 - 2011
Changes introduced with Release 11
PorphyriaSee Change Notification No. 20 - 2011
Changes introduced with Release 12
XMRVSee Change Notification No. 25 - 2011
Hepatitis CSee Change Notification No. 27 - 2011
Changes introduced with Release 13
West Nile Virus (WNV)See Change Notification No. 05 - 2012
Changes introduced with Release 14
AcneSee Change Notification No. 15 - 2012
PregnancySee Change Notification No. 16 - 2012
PsoriasisSee Change Notification No. 17 - 2012
ToxoplasmosisSee Change Notification No. 18 - 2012
Changes introduced with Release 15
West Nile Virus (WNV)See Change Notification No. 01 - 2013

Cord Blood
This page lists all changes to TDSG-CB 203 after Release 02. This page constitutes Section 2 of Appendix 1 - Changes to the Donor Selection Guidelines.
The changes are listed with the most recent change at the top.
Changes introduced with Release 03
A change was made to the version control definitions and all Issue numbering information removed.
Bleeding Disorder See Change Notification No. 18 - 2007
Changes introduced with Release 04
Tamiflu® (oseltamivir) See Change Notification No. 30 - 2009
Relenza® (zanamivir) See Change Notification No. 31 - 2009
Changes introduced with Release 05
Acupuncture See Change Notification No. 33 - 2009
Complementary Therapy See Change Notification No. 35 - 2009
Changes introduced with Release 06
Body Piercing See Change Notification No. 02 - 2010
Endoscopy See Change Notification No. 03 - 2010
Inoculation Injury See Change Notification No. 04 - 2010
Changes introduced with Release 07
West Nile Virus (WNV) See Change Notification No. 09 - 2010
Changes introduced with Release 08
Infertility See Change Notification No. 08 - 2011
Sexually Transmitted Disease See Change Notification No. 09 - 2011
Changes introduced with Release 09
West Nile Virus See
Change Notification No. 11 - 2011
Changes introduced with Release 10
Porphyria See
Change Notification No. 20 - 2011
Changes introduced with Release 11
XMRVSee Change Notification No. 25 - 2011
Hepatitis CSee Change Notification No. 27 - 2011
Changes introduced with Release 12
West Nile Virus (WNV)See Change Notification No. 05 - 2012
Changes introduced with Release 13
AcneSee Change Notification No. 15 - 2012
PsoriasisSee Change Notification No. 17 - 2012
ToxoplasmosisSee Change Notification No. 18 - 2012
Changes introduced with Release 13 Issue 02
Fertility treatment: entry replaced by link to infertility
Changes introduced with Release 14
West Nile Virus (WNV)See Change Notification No. 01 - 2013

Deceased Donors
This page lists all changes to TDSG-DD 203 after Release 02. This page constitutes Section 2 of Appendix 1 - Changes to the Donor Selection Guidelines.
The changes are listed with the most recent change at the top.
Changes introduced with Release 03
A change was made to the version control definitions and all Issue numbering information removed. No other changes where introduced.
Changes introduced with Release 04
Age See Change Notification No. 8 – 2009
Changes introduced with Release 05
Tamiflu® (oseltamivir) See Change Notification No. 28 - 2009
Relenza® (zanamivir) See Change Notification No. 29 - 2009
Changes introduced with Release 06
Acupuncture See Change Notification No. 33 - 2009
Complementary Therapy See Change Notification No. 35 - 2009
Changes introduced with Release 07
Body Piercing See Change Notification No. 02 - 2010
Inoculation Injury See Change Notification No. 04 - 2010
Changes introduced with Release 08
West Nile Virus (WNV) See Change Notification No. 09 - 2010
Changes introduced with Release 09
Immunization - Live See Change Notification No. 06 - 2011
BCG See Change Notification No. 07 - 2011
Infertility See Change Notification No. 08 - 2011
Sexually Transmitted Disease See Change Notification No. 09 - 2011
Changes introduced with Release 10
West Nile Virus See Change Notification No. 11 - 2011
Changes introduced with Release 11
Porphyria See Change Notification No. 20 - 2011
Immunosuppression See Change Notification No. 21 - 2011
Changes introduced with Release 12
XMRVSee Change Notification No. 25 - 2011
Hepatitis CSee Change Notification No. 27 - 2011
Changes introduced with Release 13
West Nile Virus (WNV)See Change Notification No. 05 - 2012
Changes introduced with Release 14
AcneSee Change Notification No. 15 - 2012
PregnancySee Change Notification No. 16 - 2012
PsoriasisSee Change Notification No. 17 - 2012
ToxoplasmosisSee Change Notification No. 18 - 2012
Changes introduced with Release 15
West Nile Virus (WNV)See Change Notification No. 01 - 2013

Live Donors
This page lists all changes to TDSG-LD 203 after Release 02. This page constitutes
Section 2 of Appendix 1 - Changes to the Donor Selection Guidelines.
The changes are listed with the most recent change at the top.
Changes introduced with Release 03
A change was made to the version control definitions and all Issue numbering information removed.
Bleeding Disorder
See Change Notification No. 18 - 2007
Changes introduced with Release 04
Tamiflu® (oseltamivir) See Change Notification No. 28 - 2009
Relenza® (zanamivir) See Change Notification No. 29 - 2009
Changes introduced with Release 05
Acupuncture See Change Notification No. 33 - 2009
Complementary Therapy See Change Notification No. 35 - 2009
Changes introduced with Release 06
Body Piercing See Change Notification No. 02 - 2010
Endoscopy See Change Notification No. 03 - 2010
Inoculation Injury See Change Notification No. 04 - 2010
Changes introduced with Release 07
West Nile Virus (WNV) See Change Notification No. 09 - 2010
Changes introduced with Release 08
Immunization - Live See Change Notification No. 06 - 2011
BCG See Change Notification No. 07 - 2011
Infertility See Change Notification No. 08 - 2011
Sexually Transmitted Disease See Change Notification No. 09 - 2011
Changes introduced with Release 09
West Nile VirusSee Change Notification No. 11 - 2011
Changes introduced with Release 10
MalariaSee Change Notification No. 14 - 2011
Changes introduced with Release 11
PorphyriaSee Change Notification No. 20 - 2011
Changes introduced with Release 12
XMRVSee Change Notification No. 25 - 2011
Hepatitis CSee Change Notification No. 27 - 2011
Changes introduced with Release 13
West Nile Virus (WNV)See Change Notification No. 05 - 2012
Changes introduced with Release 14
AcneSee Change Notification No. 15 - 2012
PregnancySee Change Notification No. 16 - 2012
PsoriasisSee Change Notification No. 17 - 2012
ToxoplasmosisSee Change Notification No. 18 - 2012
Changes introduced with Release 15
West Nile Virus (WNV)See Change Notification No. 01 - 2013
