Clinical transfusion in the medical setting

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Clinical transfusion in the medical setting

Anaemia

Features of patients seen in a medical or surgical context

Nutritional anaemias

Treatment of iron deficiency

Oral iron

Parenteral iron preparations

Precautions

Anaemia of chronic disease (ACD)

Anaemia in patients with cancer

Epoetin in anaemic cancer patients

Red cell transfusion in anaemia

What haemoglobin concentration should be maintained?

Complications of long-term red cell transfusion

Haemoglobinopathies

β-thalassaemia major

Sickle-cell disease

Haemoglobinopathy trait

Anaemia in chronic renal failure

Anaemia

Immunological sensitisation

Congenital haemostatic disorders

Patients with haemophilia A, haemophilia B and von Willebrand's disease

Initial care of a patient with haemophilia who has a bleed

Von Willebrand's disease

Bone marrow failure due to disease, cytotoxic therapy or irradiation

ABO and RhD compatibility of platelet transfusions

Platelet refractoriness

Management of refractoriness

Red cell transfusion

Prevention of transfusion-associated graft-versus-host disease

Prevention of cytomegalovirus transmission

Immunological disorders - use of immunoglobulin

Primary antibody deficiency (primary hypogammglobulinaemia)

Secondary antibody deficiency

Dosage and administration of IVIgG and SCIgG in antibody deficiency

Immunomodulatory therapy with high-dose intravenous immunoglobulin

Adverse events associated with high-dose IVIgG

Therapeutic plasma exchange

Clinical indications for therapeutic plasma exchange

Thrombotic thrombocytopenic purpura

Risks of TpE

Apheresis to remove other abnormal blood constituents

Immunoadsorption